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IAMI Trailblazer Award

The Institute for Advancing Medical Innovation (IAMI) Trailblazer Award is dedicated to supporting four targeted areas of clinical and translational research.

We will begin accepting applications for the 2020-2021 IAMI Trailblazer Award in Fall 2019. If you have questions please contact us at or 913-588-6290.

The four eligible areas are:

  1. Experimental Therapeutics Trials
    Eligible research activities include: a) clinical validation of a drug target; b) clinical pharmacology (e.g., drug metabolism, bioanalysis, pharmacokinetics, pharmacodynamics, pharmacogenomics, allometric scaling); c) clinical proof of concept of a novel therapeutic; or d) clinical proof of concept for a repurposed FDA-approved or abandoned drug. Eligible awardees must have demonstrated proof of principle in validated in vitro and/or in vivo preclinical models.

  2. Precision Medicine Informatics
    Eligible research activity includes the interrogation of existing genetic, genomic, proteomic, and metabolomics data combined with clinical data to develop precision medicine approaches to treating diseases.

  3. Biomarker Discovery and Validation
    Eligible research activities include: a) biospecimen collection; b) patient registry development; c) genetic, genomic, proteomic and metabolomic analysis of patient specimens; and d) analysis of patient specimens using established and investigational methods to discover and validate biomarkers of drug activity.

  4. Entrepreneurship Activities Consistent with IAMI's Mission
    Eligible research activities defining the investment thesis for potential product development opportunities including unmet medical need, proposed solution, market, competitive landscape, patent position and strategy, summary of existing data, product development and regulatory planning, marketing and licensing strategy, as well as support for obtaining key opinion leader input, will be supported.

The Frontiers IAMI Trailblazer Award seeks applications from all diseases and encourages clinical and translational research projects that are integrated across the lifespan, across Frontiers institutions, and across CTSA hubs. Proposals for a Frontiers IAMI Trailblazer Award will be reviewed by the Institute for Advancing Medical Innovation leadership and Frontiers leadership and selection will be confirmed by the Frontiers Operations Group, a leadership group representing all of Frontiers' institutional partners. Funds may not be used for investigator salary support or travel. Support for study team personnel will be considered.

Please be sure to identify the specific aim(s) that map to one of the four eligible areas described in this announcement. Proposals should include the following sections: background, significance, specific aims, and innovation/benefit. Proposals should be five pages or less in length and include a detailed project plan with defined milestones and go/no go decisions. Awardees must express a willingness to work closely with the IAMI Navigator to ensure adequate project management support is provided.

A total of $50,000 is available; we anticipate funding one or two projects. Opportunities to leverage Frontiers IAMI Trailblazer Awards with additional resources are considered proposal strengths. Indirect/Facilities and Administration costs are not allowed for Frontiers Trailblazer awards.

All funds awarded for 2019-2020 must be spent by June 30, 2020.

Last modified: Jun 04, 2019