Clinical Studies and Recruitment Support
Frontiers: University of Kansas Clinical and Translational Science Institute (KU CTSI) is designed to ensure that investigators conduct clinical and translational research that meet the highest standards by supporting them with efficient, timely and valuable resources to meet their research aims.
Supports multi-site trials:
- SMART IRB
- National Trial Innovation Network
- Space & personnel to conduct research
- Participant recruitment registries
- Recruitment & retention strategies
With the support of a dedicated Frontiers Navigator, investigators can develop, initiate, and complete studies using Frontiers-affiliated Clinical and Translational Science Units (CTSUs). These state-of-the-art facilities provide space for researchers to see patients who are enrolled in clinical trials. The Navigator assists investigators with preparing for scientific review, seeking approvals (e.g., IRB review), budget development and fostering needed collaborations. The Navigator guides PIs and study teams through study start-up by assessing feasibility, identifying necessary resources and staff, and linking with other resources such as regulatory experts. The highly trained staff of the CTSUs ensure that participants have a positive experience and that protocols are followed, thereby contributing to better outcomes and successful clinical trials.
Frontiers/Pioneers Research Recruitment Registries and ResearchMatch.org
Frontiers Recruitment and Trial Innovation Unit (RTIU) is dedicated to speeding trial completion by streamlining trial start-up processes and improving processes for recruiting and retaining participants. The Frontiers / Pioneers Research Recruitment Registries provide researchers with contact information for people who have enrolled in these registries and appear to meet study criteria according to EHR and medical history information. There are currently over 60,000 patients from the KU Health System and the community who have agreed to be contacted for approved research studies. ResearchMatch.org is a national resource to support participant engagement for Frontiers investigators. This registry was developed by institutions affiliated with the Clinical and Translational Science Awards (CTSA) program, and provides access to over 92,000 people who are trying to find research studies and clinical trials and connects them to researchers who are looking for volunteers. The RTIU Navigator can provide resources on how to register and sign up for training for any of these recruitment resources, and can provide consultation regarding best practices for recruitment.
Frontiers has deep clinical trials experience especially in designing and running multi-site trials. Since 2013, Frontiers has been streamlining oversight and eliminating duplicate review of cross-institutional projects, and is able to fully implement the NIH policy for single IRB review. Frontiers can assist with budget and contract negotiations to establish collaborative agreements and sub-awards. Using the Accelerated Confidential Disclosure Agreement, Master Data Sharing Agreement and External Institutional Collaborator Agreement supports efficient multi-center trial studies.
Trial Innovation Network
The Trial Innovation Network (TIN) is a new collaborative initiative within the CTSA Program and is comprised of three key organizational partners – the CTSA Program Hubs, the Trial Innovation Centers (TICs)and the Recruitment Innovation Center (RIC). The TIN is innovating to address critical roadblocks in clinical research by offering investigators access to master contracting agreements, quality by design approaches and a focus on evidence-based strategies to recruitment and patient engagement. Frontiers investigators will benefit from their technical assistance and access to TIN resources.
Oct 04, 2018